Approximately 30 million people of all ages and genders suffer from an eating disorder in the U.S.
~ National Association of Anorexia Nervosa and Associated Disorders, Inc.
Written by: Dr Kim Langdon MD
Reviewed by: Dr. RY Langham PhD
Table of Contents
Bulimia nervosa is a set of repetitive behaviors intended to rid the body of the excess calories consumed during eating binges.
These compensatory behaviors include:
A person with bulimia may use one or all of these applications to enact this eating disorder.
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) uses five key characteristics to classify bulimia nervosa: 
Bulimia nervosa is characterized by the following symptoms: [2, 3, 4]
Below are some charts from the National Institute of Mental Health describing the prevalence of Bulimia in the adult population.
> Neurological [22, 23, 24]
Serotonin is linked to weight regulation and eating behaviors. There have been documented cases of elevated serotonin in the cerebral spinal fluid in patients with anorexia nervosa and bulimia nervosa. Lower levels of norepinephrine are also associated with anorexia nervosa. Dopamine activity is also linked to body image distortion, and the D4 receptor gene malfunction, which is associated with both bulimia nervosa and binge-eating.
Hormone changes may be the result or possible cause of bulimia. There are complex irregular interactions between neuropeptide Y (NP-Y), peptide Y (PYY), and anorexia-causing factors such as cholecystokinin (CCK) and beta-endorphin. Furthermore, people with bulimia nervosa have reduced beta-endorphin and CCK levels.
No definite inheritance patterns have been identified in bulimia, but a familial component appears to be involved in the development of eating disorders. There have been proposed genetic links on chromosomes 1, 3, and 10p related to bulimia nervosa. Chromosome 10p may also be linked to obesity, in addition to bulimia nervosa.
In addition, suppression of cholecystokinin (CCK) and ghrelin, following meals may occur in individuals, suffering from bulimia nervosa. Therefore, researchers believe that this predisposing factor could lead to an impaired sense of satiety (sense of fullness) and/or the emergence of an eating disorder. 
> Developmental Factors
Developmental factors that could lead to bulimia include: childhood and/or separation anxiety.  It also involves a history of childhood trauma and neglect, including subtle degrees of psychological abuse, teasing, and other interactions that generate self-doubt also appear to play a role in the development of bulimia nervosa.
> Sociocultural Factors
Potential precipitating events that can trigger binge/purge eating cycles are: increased anxiety, emotional tension, boredom, environmental food triggers, alcohol use, substance abuse, and fatigue.
Moreover, people, who severely restrict their food intakes, may experience sudden and intense eating binges (in an “all or none” fashion).
Furthermore, both anorexia nervosa and bulimia nervosa sufferers experience intense concerns about weight and appearance.
> Psychological Factors
Self-esteem, self-control issues, impulsivity, perfectionism, body image distortion, susceptibility to triggers, centered on dieting and weight loss, and poor coping skills are all associated with bulimia.
Bulimia nervosa is more common among people, whose occupations or hobbies requires rapid weight loss or weight gain, such as with wrestlers and competitive bodybuilders.  In addition, athletes like track runners and gymnasts are more prone to eating disorders, than athletes like golfers or tennis players. 
For instance, a female athlete, who suffers from three or more eating disorders, hypothalamic amenorrhea (a lack of menstrual cycles and/or anovulation – absent ovulations), and osteoporosis, becomes well-known – mostly because in her occupation, slim bodies are of great importance.
Moreover, female gymnasts, divers, long distance runners, and figure skaters have a higher risk of developing eating disorders, partly due to their occupations. It is important to note that male athletes like wrestlers, cyclists, weightlifters also experience eating disorders. Furthermore, actors/actresses, models, and ballet dancers have a higher risk of developing anorexia or bulimia, than those in careers that do not focus on body shape and appearance. 
> Psychiatric complications
Studies indicate that patients with bulimia nervosa have a higher risk of developing major depressive disorder, substance abuse, anxiety disorders, bipolar II disorder, and experiencing sexual abuse.
In addition, mortality from suicide and morbidity associated with depression and poor impulse control – i.e. substance abuse, sexually-transmitted diseases, unintended pregnancies, and accidental injuries can all contribute to the development of eating disorders like bulimia.
Lastly, those with bulimia nervosa, depression, and an alcohol dependency have a very high risk of suicide, especially in those, who excessively exercise. [10, 11]
> Medical complications
The mortality rate for bulimia nervosa is slightly lower than for anorexia nervosa (3.9% vs 4.0%, respectively. 
Rare medical complications can occur, such as: delayed emptying of the stomach and/or stomach/esophageal dilation.
Although these complications are rare, they can be fatal if the stomach or esophagus ruptures. In addition, chronic ipecac can result in an enlarged, malfunctioning heart.
Removing the familial focus on physical appearance is the best way to prevent atypical thought processes that put people at-risk of developing eating disorders. In addition, programs that educate young people about healthy nutrition, exercise, and weight loss, while promoting self-esteem can also help prevent bulimia and other eating disorders.
Bulimics typically have feelings of guilt, and therefore, are less likely to deny that a problem exists, when interviewed by an understanding professional. In addition, a high suspicion index is required when a young person appears to be depressed or extremely weight-conscious.
> A set of screening questions, such as the SCOFF questionnaire , can quickly help determine the need for further in-depth questioning.
The SCOFF questionnaire includes the following 5 questions:
> The Eating Disorder Screen for Primary Care (ESP) questionnaire is an alternative screening tool that contains the following 5 questions: 
> The Eating Attitudes Test (EAT) is a self-report screening instrument that patients can complete, in the waiting room, while waiting to see a health care professional. 
Initial care for bulimia nervosa is usually provided in outpatient settings. Factors like significant metabolic abnormalities, medical complications, risk of suicide, failed outpatient treatment, and inability to care for self may indicate a need for inpatient services. For guidelines on patient-level-of-care, refer to the APA Practice Guidelines for Eating Disorders. 
Bulimia nervosa is best managed using an interdisciplinary approach. A primary care provider, psychiatrist, psychotherapist, and nutritionist/dietitian should be involved in the patient’s care. If the psychiatrist is unskilled in this area, a psychotherapist with expertise in eating disorders should be consulted. A nutritionist/registered dietitian should provide the patient with dietary review and nutritional rehabilitation counseling, and he/she should receive proper dental care.
The goals of treatment are as follows: 
According to the National Institute of Mental Health, only 43.2% of people with the disorder receive treatment.
Eating disorders tend to arise within a cultural context that places an extremely high value on “thinness” placing unreasonable expectations on physical appearance.
Awareness of the cultural and social forces, along with education for children and their parents on attitudes and behaviors that foster eating disorders may reduce the occurrence of eating disorders. A family can find learning opportunities through primary care, athletics, and in educational settings.
More so, some schools offer programs that emphasize health, fitness and a wide-range of physical and psychological competences. Research suggests that these programs may reduce the development of the negative attitudes, associated with eating disorders, in vulnerable school-age children.  Therefore, experts suggest that the earlier bulimia is recognized and treated, the better the chances for recovery.
Lastly, factors like the length of the symptoms, the age of the individual at the start of treatment, severe weight loss, and/or clinical depression are all associated with a poorer prognosis. The rate of relapse with all eating disorders is fairly high, and usually triggered by social stress. It is important to note that bulimia’s mortality rate is approximately 4-percent.
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